Code and Computational Resources

Here you can find open-source software and data resources developed by the Neuro-SC Lab to facilitate single-cell omics analysis.

Software Packages

SCORPION (Spatial-Cell Omics R-based Pipeline for Integration)

A comprehensive R package built on the Tidyverse framework for robust and reproducible integration of single-cell RNA-seq and Spatial Transcriptomics datasets.

Reference: Student A, Your Name, Ph.D. (2023). Genome Biology.

GitHub Repository View Publication
Microglia Subtype Classifier (Python)

A Python utility using machine learning models (Random Forest/XGBoost) to classify microglial cell states (e.g., homeostatic, DAM, inflammatory) based on scRNA-seq profiles.

Reference: Student B, Your Name, Ph.D. (2024). Cell.

GitHub Repository

Datasets

Raw and processed data from our major publications are deposited in public repositories, with links provided below.

Single-Cell Web Resource Directory

A curated list of commonly used public databases and interactive portals for quick exploration and reuse.

CZ CELLxGENE Discover

A large-scale collection of public single-cell datasets with metadata search and expression visualization.

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Human Cell Atlas Data Portal

The official Human Cell Atlas portal for cross-tissue reference atlas search and download.

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Broad Single Cell Portal

Browse clustering results, metadata, and downloadable data across multiple biological domains.

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UCSC Cell Browser

Interactive embeddings for many published datasets, ideal for quick marker and cluster inspection.

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Tutorials Worth Bookmarking

Core learning resources across the R and Python ecosystems for onboarding and advanced practice.